WEKO3
アイテム
Vitamin E Supplementation Attenuates Strenuous Exercise Induced DNA Damage and Lipid Peroxidation of the Liver in Rats
https://doi.org/10.15112/00005039
https://doi.org/10.15112/000050399ed6a5dd-9942-4d1b-a0d1-6b5738525247
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PDF (223.1 kB)
|
|
| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2008-01-01 | |||||||||
| タイトル | ||||||||||
| タイトル | Vitamin E Supplementation Attenuates Strenuous Exercise Induced DNA Damage and Lipid Peroxidation of the Liver in Rats | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 8-hydroxydeoxyguanosine | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | thiobarbituric acid reactive substance | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | α-tocopherol | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | strenuous endurance exercise | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.15112/00005039 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| ページ属性 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | P(論文) | |||||||||
| 著者名(英) |
Kinoshita, Sachifumi
× Kinoshita, Sachifumi
× Tsuji, Etsuko
|
|||||||||
| 著者所属(英) | ||||||||||
| en | ||||||||||
| Department of Health System Management, Hyogo University | ||||||||||
| 著者所属(英) | ||||||||||
| en | ||||||||||
| Department of Nutrition Management, Hyogo University | ||||||||||
| 抄録(英) | ||||||||||
| en | ||||||||||
| This study was designed to investigate the effects of vitamin E supplementation on exercise-induced DNA damage and lipid peroxidation in rat livers. Male Wistar rats were divided into three groups: a sedentary control (CON) group fed a control diet, and two exercise groups, one fed a control diet (EX) and the other fed a vitamin E supplemented diet (EX+VE). The exercise groups performed treadmill runs for 4 weeks, 5 days a week for 30 minutes per day. Thiobarbituric acid reactive substance (TBARS) levels in the EX+VE group were significantly lower than the EX group (p<0.05). Hepatic 8 - hydroxydeoxyguanosine (OHdG) in the EX+VE group was also significantly lower than the EX group (p<0.05). The results showed that there was oxidative damage to lipids and DNA due to exhausting exercise together with a decrease in α-tocopherol levels in the liver due to lipid peroxidation. However, when high levels of vitamin E were added to the diet, TBARS levels in the liver significantly decreased and the increase in hepatic 8-OHdG levels was suppressed. These results suggest that intake of antioxidants plays an important role in protection against oxidative stress of the liver when performing strenuous exercise. | ||||||||||
| 書誌情報 |
en : Kawasaki journal of medical welfare 巻 14, 号 1, p. 1-7, 発行日 2008 |
|||||||||
| 公開者 | ||||||||||
| 出版者 | 川崎医療福祉学会 | |||||||||
| 雑誌書誌ID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA11108172 | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 1341-5077 | |||||||||
