{"created":"2023-06-19T10:03:22.711004+00:00","id":5046,"links":{},"metadata":{"_buckets":{"deposit":"969216c1-3ff3-403a-b432-5e5237c018ef"},"_deposit":{"created_by":17,"id":"5046","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"5046"},"status":"published"},"_oai":{"id":"oai:kwmw.repo.nii.ac.jp:00005046","sets":["76:90:104"]},"author_link":["21037","21038"],"control_number":"5046","item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"Kawasaki journal of medical welfare","bibliographic_titleLang":"en"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kinoshita, Sachifumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"21037","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Etsuko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"21038","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15112/00005039","subitem_identifier_reg_type":"JaLC"}]},"item_1_publisher_23":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"川崎医療福祉学会"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11108172","subitem_source_identifier_type":"NCID"}]},"item_1_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-5077","subitem_source_identifier_type":"PISSN"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Health System Management, Hyogo University"},{"subitem_text_language":"en","subitem_text_value":"Department of Nutrition Management, Hyogo University"}]},"item_1_textarea_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"This study was designed to investigate the effects of vitamin E supplementation on exercise-induced DNA damage and lipid peroxidation in rat livers. Male Wistar rats were divided into three groups: a sedentary control (CON) group fed a control diet, and two exercise groups, one fed a control diet (EX) and the other fed a vitamin E supplemented diet (EX+VE). The exercise groups performed treadmill runs for 4 weeks, 5 days a week for 30 minutes per day. Thiobarbituric acid reactive substance (TBARS) levels in the EX+VE group were significantly lower than the EX group (p<0.05). Hepatic 8 - hydroxydeoxyguanosine (OHdG) in the EX+VE group was also significantly lower than the EX group (p<0.05). The results showed that there was oxidative damage to lipids and DNA due to exhausting exercise together with a decrease in α-tocopherol levels in the liver due to lipid peroxidation. However, when high levels of vitamin E were added to the diet, TBARS levels in the liver significantly decreased and the increase in hepatic 8-OHdG levels was suppressed. These results suggest that intake of antioxidants plays an important role in protection against oxidative stress of the liver when performing strenuous exercise."}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-01-29"}],"displaytype":"detail","filename":"04_kinoshita.pdf","filesize":[{"value":"223.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","url":"https://kwmw.repo.nii.ac.jp/record/5046/files/04_kinoshita.pdf"},"version_id":"a71e11a7-b012-48d5-81f9-4f4f593197bc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"8-hydroxydeoxyguanosine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"thiobarbituric acid reactive substance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"α-tocopherol","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"strenuous endurance exercise","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Vitamin E Supplementation Attenuates Strenuous Exercise Induced DNA Damage and Lipid Peroxidation of the Liver in Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Vitamin E Supplementation Attenuates Strenuous Exercise Induced DNA Damage and Lipid Peroxidation of the Liver in Rats","subitem_title_language":"en"}]},"item_type_id":"1","owner":"17","path":["104"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-01-01"},"publish_date":"2008-01-01","publish_status":"0","recid":"5046","relation_version_is_last":true,"title":["Vitamin E Supplementation Attenuates Strenuous Exercise Induced DNA Damage and Lipid Peroxidation of the Liver in Rats"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-12-09T01:35:36.522877+00:00"}