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Caffeine Induced Ca-release Dependence on the Bound Ca on the Outersurface Membrane of the Sarcoplasmic Reticulum Skeletal Muscle
https://doi.org/10.15112/00000055
https://doi.org/10.15112/00000055eca90dfe-5dac-472a-82d0-629db27b2256
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PDF (493.3 kB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||||
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| 公開日 | 1996-01-01 | |||||||
| タイトル | ||||||||
| タイトル | Caffeine Induced Ca-release Dependence on the Bound Ca on the Outersurface Membrane of the Sarcoplasmic Reticulum Skeletal Muscle | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | skeletal muscle | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | caffeine | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | sarcoplasmic reticulum Ca-release channel | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | procaine. | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| ID登録 | ||||||||
| ID登録 | 10.15112/00000055 | |||||||
| ID登録タイプ | JaLC | |||||||
| ページ属性 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | P(論文) | |||||||
| 著者名(英) |
Nishijima, Hiroaki
× Nishijima, Hiroaki
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department of Health and Sports Sciences, Faculty of Medical Professions, Kawasaki University of Medical Welfare | ||||||||
| 抄録(英) | ||||||||
| en | ||||||||
| It is known that the Ca release channels/RyR binding sites of skeletal muscle sarcoplasmic reticulum is modulated by caffeine. Caffeine potentiates Ca sensitivity in the Ca induced Ca release (CICR) channels. The aim of this experiment was to investigate whether Ca uptake in the FSR and Ca release from the FSR were changed by the bound Ca on the outer surface of the FSR membrane. When FSR was treated with low concentrations of caffeine, Ca release from the FSR was activated and the Ca bound on the outer surface membrane of the FSR was suppressed. However, when FSR was treated with low concentrations of procaine, Ca release from the FSR by caffeine was inhibited. Also, the Ca bound on the outer surface membrane of procaine treated FSR was not suppressed by caffeine and EGTA. It was suggested that the Ca release sites/RyR binding sites were accelerated with the increases of the stored Ca2+ and the bound Ca on the outer surface membrane of the SR, and that the inhibition of CICR by procaine was induced by the lock of the bound Ca on the outer surface membrane of the SR. | ||||||||
| 書誌情報 |
en : Kawasaki journal of medical welfare 巻 2, 号 2, p. 133-140, 発行日 1996 |
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| 公開者 | ||||||||
| 出版者 | 川崎医療福祉学会 | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA11108172 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 1341-5077 | |||||||
