Item type |
紀要論文(ELS) / Departmental Bulletin Paper(1) |
公開日 |
2005-01-01 |
タイトル |
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タイトル |
Heat-killed Propionibacterium Acnes Up-regulates Toll-like Receptor 4 on Macrophages |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
propionibacterium acnes |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
toll-like receptor 4 |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
lipopolysaccharide |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
ID登録 |
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ID登録 |
10.15112/00005077 |
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ID登録タイプ |
JaLC |
ページ属性 |
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内容記述タイプ |
Other |
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内容記述 |
P(論文) |
著者名(英) |
Shiva, Daisuke
Matsumoto, Takashi
Yano, Hiromi
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著者所属(英) |
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en |
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Doctoral Program in Health Science, Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare |
著者所属(英) |
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en |
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Master's Program in Health and Sports Science, Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare |
著者所属(英) |
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en |
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Department of Health and Sports Science, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare |
抄録(英) |
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en |
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It is known that heat-killed Propionibacterium acnes (P.acnes) induces lipopolysaccharide (LPS) hypersensitivity. However, effect of the P.acnes on expression of Toll-like receptor (TLR) 4 remains unclear. To determine whether or not TLR4 expression of macrophages can be changed by the P.acnes stimulation, TLR4 of RAW264.7 cells as measured after the P.acnes stimulation in vitro. Furthermore, the P.acnes-treated mice were measured as to the expression of TLR4 mRNA in the liver. The P.acnes treatment increased the TLR4 expression on RAW264.7 cells. The P.acnes-treated mice also were expressed as TLR4 mRNA in the liver. These results may suggest that an up-regulation of TLR4 on macrophages can be induced by heat-killed P.acnes treatment. |
書誌情報 |
en : Kawasaki journal of medical welfare
巻 11,
号 1,
p. 9-13,
発行日 2005
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公開者 |
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出版者 |
川崎医療福祉学会 |
雑誌書誌ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11108172 |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1341-5077 |