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Autonomic Responses Associated with Severe Gagging Elicited by Stimulation of the Superior Laryngeal Nerve in Rats
https://doi.org/10.15112/00005009
https://doi.org/10.15112/00005009f5961807-cbfd-47b5-8704-fdd097bbb0a0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PDF (561.6 kB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||||||
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| 公開日 | 2012-01-01 | |||||||||
| タイトル | ||||||||||
| タイトル | Autonomic Responses Associated with Severe Gagging Elicited by Stimulation of the Superior Laryngeal Nerve in Rats | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | severe gagging | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | esophageal pressure | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | blood pressure | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | vagal nerve | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | muscarinic acetylcholine receptor | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.15112/00005009 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| ページ属性 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | P(論文) | |||||||||
| 著者名(英) |
Yamagata, Ryuzo
× Yamagata, Ryuzo
× Koga, Tomoshige
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| 著者所属(英) | ||||||||||
| en | ||||||||||
| Department of Rehabilitation, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare | ||||||||||
| 著者所属(英) | ||||||||||
| en | ||||||||||
| Department of Rehabilitation, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare | ||||||||||
| 抄録(英) | ||||||||||
| en | ||||||||||
| Tactile stimulation of the pharyngo-laryngeal region elicits severe gagging, which is characterized by simultaneous contraction of the costal diaphragm and abdominal muscles. While severe gagging is associated with problems in oral feeding in children, routine dental treatment and gastrointestinal endoscopy, little is known about the neural mechanism of this reflex. In the present study using decerebrate rats, we observed dynamic changes in the activities of the costal and crural diaphragm, abdominal muscles, and infrahyoid muscles, and in pharyngeal and esophageal pressure during severe gagging, and determined the most suitable stimulation of the superior laryngeal nerve (SLN) for induction. High-frequency stimulation of the SLN at 50 Hz (30 μA, 50 pulses) elicited severe gagging in all of the rats. Severe gagging had the following characteristics: 1) simultaneous activation of the costal diaphragm and abdominal muscles, but relaxation of the crural diaphragm; 2) infrahyoid muscle contraction and temporary decrease in pharyngeal pressure; 3) retrograde contraction of esophageal striated muscles; and 4) decrease of blood pressure, which was mediated by a vagal muscarinic pathway. The identification of characteristic changes in respiratory muscles and autonomic responses should assist future studies on the mechanism of severe gagging. | ||||||||||
| 書誌情報 |
en : Kawasaki journal of medical welfare 巻 18, 号 1, p. 1-11, 発行日 2012 |
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| 公開者 | ||||||||||
| 出版者 | 川崎医療福祉学会 | |||||||||
| 雑誌書誌ID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA11108172 | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 1341-5077 | |||||||||
