| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-05-23 |
| タイトル |
|
|
タイトル |
Emetic stimulation inhibits the swallowing reflex in decerebrate rats. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
swallowing reflex |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hypoxia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gastric distension |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
emetic drug |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ページ属性 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
P(論文) |
| 著者名(英) |
Kurozumi, Chiharu
Yamagata, Ryuzo
Himi, Naoyuki
Koga, Tomoshige
|
| 抄録(英) |
|
|
|
en |
|
|
The effects of emetic stimulation on the swallowing reflex were investigated in decerebrated rats. Hypoxia, gastric distension and LiCl administration were used as emetic stimulations. The swallowing reflex was elicited by electrical stimulation of the superior laryngeal nerve (SLN, 20 Hz, 3-5 V, 0.3 ms duration) for 20 s. To examine the effect of hypoxia, nitrogen gas was inhaled under artificial ventilation. There were significantly fewer swallows during a decrease in PO(2) than under air ventilation (p<0.05). The number of swallows during 3-ml stomach distension was significantly lower than that before distension (p<0.05). Intravenous administration of LiCl (100 mg/kg) also significantly reduced the number of swallows (p<0.05). The combination of SLN stimulation and emetic stimuli occasionally produced burst activity of abdominal muscles, which might be associated with the gag reflex. Both the gag and swallowing reflexes are well known to be mediated by the nucleus of the solitary tract. The physiological roles of the gag reflex and the swallowing reflex are considered to be reciprocal. Taken together, these results suggest that emetic stimulation inhibits the swallowing pattern generator via the nucleus of the solitary tract, which in turn facilitates the gag reflex. |
| 書誌情報 |
en : Autonomic neuroscience : basic & clinical
巻 140,
号 1-2,
p. 24-29,
発行日 2008-06
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| 公開者 |
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出版者 |
Author |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1566-0702 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11470577 |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.autneu.2008.02.001 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
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